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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
09:44

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Published on: January 25, 2016

[Clinical analysis on syphilis with sensorineural deafness].

Shaoyan Zhang1, Yaodong Xu, Jian Gong

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510120, China.

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
|October 9, 2008
PubMed
Summary

Syphilis can cause sensorineural deafness and tinnitus, often missed in diagnosis. Early lab tests are crucial for identifying this syphilis complication when hearing loss has unknown causes.

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Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Neurology

Background:

  • Syphilis is a sexually transmitted infection with diverse clinical manifestations.
  • Sensorineural hearing loss and tinnitus are potential, though infrequently recognized, symptoms of neurosyphilis.

Observation:

  • This study analyzed three patients presenting with sensorineural deafness and tinnitus attributed to syphilis.
  • Diagnostic criteria included serological tests like Rapid Plasma Reagin (RPR) and Treponema Pallidum Particle Agglutination (TPPA).
  • Two patients had prior syphilis diagnosis and treatment, while all presented with unexplained hearing or tinnitus symptoms.

Findings:

  • Two patients tested positive for both RPR and TPPA, with one testing RPR negative but TPPA positive.
  • Two cases exhibited sudden sensorineural deafness and tinnitus; one had tinnitus with high-frequency hearing loss.
  • Therapeutic interventions did not result in improvement of hearing loss levels in the observed cases.

Implications:

  • Sudden hearing loss and tinnitus can be indicative of syphilis-related sensorineural deafness.
  • The condition is prone to diagnostic delays, underscoring the need for thorough etiological investigation.
  • Laboratory examinations are essential for diagnosing hearing loss, tinnitus, or nystagmus of unknown origin, particularly in suspected syphilis cases.