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Pelvic inflammatory disease with Tc-99m ciprofloxacin imaging
Moon Whan Im1, Wonsick Choe, Sung Ook Hwang
1Department of Obstetrics and Gynecology, Inha University School of Medicine, Incheon, Korea. mwim@inha.ac.kr
Abstract:
The clinical diagnosis of pelvic inflammatory disease (PID) is inexact. There are multiple potential symptoms and signs ascribable to PID as predicted by areas of inflammatory involvement. No symptoms or signs are pathognomonic for PID. The authors describe single photon emission computed tomography (SPECT) images of technetium-99m ((99m)Tc) ciprofloxacin imaging of patients with PID that showed foci of significantly increased uptake in the regions corresponding to the areas of clinical symptoms. We report two such cases of PID. We undertook physical exams, complete blood count, erythrocyte sedimentation rate, C-reactive protein, Gram stains, wet smears, cultures, Mycoplasma genetic studies, Chlamydia cultures, and SPECT before treatment. During treatment we took laparoscopies, hysteroscopies, biopsies, and cultures. After the treatment, we repeated the same exams. (99m)Tc ciprofloxacin imaging is considered valuable in persons with symptoms of PID in whom diagnosis is difficult.
Insights
Diagnosing pelvic inflammatory disease (PID) can be challenging. Technetium-99m ((99m)Tc) ciprofloxacin SPECT imaging shows increased uptake in affected areas, aiding diagnosis in difficult cases.
Area of Science:
- Nuclear medicine
- Diagnostic imaging
- Infectious disease
Background:
- Clinical diagnosis of pelvic inflammatory disease (PID) is often inexact due to varied symptoms.
- No single symptom or sign is definitively pathognomonic for PID.
Observation:
- This study describes the use of single photon emission computed tomography (SPECT) with technetium-99m ((99m)Tc) ciprofloxacin.
- SPECT imaging revealed foci of significantly increased radiotracer uptake in patients diagnosed with PID, correlating with clinical symptoms.
Findings:
- Two cases of PID are presented where (99m)Tc ciprofloxacin SPECT imaging demonstrated localized areas of increased uptake.
- Diagnostic evaluations included physical exams, blood tests, microbiological studies, and imaging before and after treatment.
Implications:
- (99m)Tc ciprofloxacin SPECT imaging appears valuable for diagnosing PID, particularly in cases where clinical diagnosis is difficult.
- This imaging modality may improve diagnostic accuracy and guide treatment decisions for PID.
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