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Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
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Published on: October 25, 2015

Ovine-associated Q fever.

D Webster1, D Haase, T J Marrie

  • 1Division of Infectious Diseases, Department of Medicine, Saint John Regional Hospital, Saint John, New Brunswick, Canada. webdu@reg2.health.nb.ca

Epidemiology and Infection
|October 9, 2008
PubMed
Summary

Q fever infection in Nova Scotia was linked to sheep exposure, a new risk factor. Half the sheep flock showed antibodies, indicating widespread Coxiella burnetii infection.

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Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Zoonotic Diseases

Background:

  • Q fever infection traditionally linked to cats and kittens in Atlantic Canada.
  • Previous understanding of Q fever transmission routes in the region.

Observation:

  • First documented case of Q fever in Nova Scotia acquired through direct sheep exposure.
  • Investigation of a sheep flock associated with the human case.

Findings:

  • Serosurvey revealed 50% (23/46) of sheep were seropositive for Coxiella burnetii phase II antibodies.
  • High antibody titers (1:64 and 1:128) detected, particularly in nursing ewes.
  • No Coxiella burnetii DNA detected in milk samples via PCR.

Implications:

  • Highlights sheep as a potential reservoir and transmission source for Q fever in Nova Scotia.
  • Suggests a need to re-evaluate traditional risk factors for Q fever acquisition in the region.
  • Emphasizes the importance of veterinary surveillance for zoonotic diseases in livestock.