Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Drug Elimination: Non-Renal Routes01:23

Drug Elimination: Non-Renal Routes

The liver plays a pivotal role in eliminating drugs and their metabolites, primarily through a process known as biliary excretion. This process involves the hepatocytes, the primary cells in the liver that generate bile. A range of transporters actively expels polar drugs or hydrophilic drug metabolites into the bile, which transports the drugs and metabolites into the small intestine. From here, they are eventually expelled from the body through feces. In some instances, the original drug or a...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Progress Toward Eradication of Dracunculiasis (Guinea Worm Disease) - Worldwide, January 2024-June 2025.

MMWR. Morbidity and mortality weekly report·2025
Same author

Leaving no one behind in NTD programmes: lessons from implementing a risk assessment tool.

International health·2025
Same author

Revisiting the epidemiology of schistosomiasis and soil-transmitted helminthiasis in Chad: insights for improved interventions.

International health·2025
Same author

Towards elimination of genital schistosomiasis in Africa: Outlining strategic public health objectives and measures to protect future generations.

Parasitology·2025
Same author

Assessing the need to implement mass drug administration against Wuchereria bancrofti infection using both human serology and xenomonitoring in the urban conurbation of Monrovia, Liberia.

PLoS neglected tropical diseases·2025
Same author

The changing neglected tropical disease landscape in Africa: implications for policy, practice, and strengthening health systems.

Health affairs scholar·2025

Related Experiment Video

Updated: Jun 29, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

Dracunculiasis eradication: neglected no longer.

Donald R Hopkins1, Ernesto Ruiz-Tiben, Philip Downs

  • 1The Carter Center, Atlanta, Georgia 30307, USA. sdsulli@emory.edu

The American Journal of Tropical Medicine and Hygiene
|October 9, 2008
PubMed
Summary
This summary is machine-generated.

The global Dracunculiasis Eradication Program has eliminated Guinea worm disease transmission in 15 countries. Efforts continue to eradicate the remaining cases by 2009.

More Related Videos

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Related Experiment Videos

Last Updated: Jun 29, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Area of Science:

  • Global Health
  • Infectious Disease Control
  • Parasitology

Background:

  • Dracunculiasis, or Guinea worm disease, was endemic in 20 countries in 1986.
  • Significant progress has been made in its global eradication.
  • The disease poses a significant public health challenge in affected regions.

Purpose of the Study:

  • To summarize the status of the global Dracunculiasis Eradication Program as of early 2008.
  • To highlight progress and remaining challenges in Guinea worm disease eradication efforts.
  • To provide an update on transmission and case numbers worldwide.

Main Methods:

  • Data compilation from national eradication programs.
  • Analysis of reported dracunculiasis cases and endemic villages.
  • Review of transmission status in remaining affected countries.

Main Results:

  • Transmission eliminated in 15 of the 20 endemic countries by end of 2007.
  • Worldwide reported cases reduced to 9,585 in 2007.
  • Nigeria and Niger nearing elimination; Sudan, Ghana, and Mali targeting 2009 interruption.

Conclusions:

  • The global Dracunculiasis Eradication Program is nearing its goal.
  • Sustained efforts are crucial to interrupt remaining transmission.
  • Interruption of Guinea worm disease transmission is achievable with continued commitment.