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Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Bone graft harvest using a new intramedullary system.
Mohan V Belthur1, Janet D Conway, Gaurav Jindal
1SPARSH Hospital, Bangalore, India.
Clinical Orthopaedics and Related Research
|October 9, 2008
Summary
Harvesting autogenous bone graft using an intramedullary (IM) system from long bones offers a safer alternative to iliac crest bone grafting (ICBG). This method results in significantly less donor site pain for patients.
Area of Science:
- Orthopedic Surgery
- Regenerative Medicine
- Biomaterials
Background:
- Autogenous bone graft is crucial for skeletal reconstruction.
- Traditional iliac crest bone graft (ICBG) harvesting is associated with significant donor site morbidity.
- Intramedullary (IM) harvesting systems offer a potential alternative for bone graft procurement.
Purpose of the Study:
- To evaluate the safety and efficacy of IM harvesting of autogenous bone graft from long bones.
- To compare donor site pain and graft volume between IM harvesting and ICBG.
- To document complications associated with the IM harvesting technique.
Main Methods:
- Retrospective comparative study (Level III evidence).
- Bone graft volume measured from IM canals of femur and tibia.
- Patient surveys assessed pain intensity and frequency post-harvest.
- Comparison between 41 patients undergoing IM harvest and 40 patients undergoing ICBG.
Main Results:
- The IM harvest group reported significantly lower postoperative pain scores compared to the ICBG group.
- Mean graft volume for the IM harvest group was 40.3 mL (range, 25-75 mL).
- No specific complications related to the IM harvesting technique were detailed, implying safety with meticulous technique.
Conclusions:
- Intramedullary harvesting of autogenous bone graft from long bones is a safe and effective alternative to ICBG.
- This technique offers reduced donor site morbidity, specifically lower pain levels.
- Meticulous surgical technique is essential for safe and successful IM bone graft harvesting.

