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Updated: Jun 29, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
[Studies on flavonoid glycosides of Sarcandra glabra]
Ming-ju Huang1, Guang-yao Zeng, Jian-bing Tan
1School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
Objective:
To in vestigate the chemical constituents of Sarcandra glabra and obtain a more comprehensive understanding on its effective components.
Method:
The constituents were isolated by various column chromatographic method and their structures were elucidated by physico-chemical properties and spectroscopic analysis.
Result:
Five flavonoid glycosides were isolated and identified as kaempferol-3-O-beta-D-glucuronide (1), quercetin-3-O-alpha-D-glucuronide (2), quercetin-3-O-beta-D-glucuronopyranoside methyl ester (3), 5, 7, 4'-trihydroxy-8-C-beta-D-glucopyranosyl flavanone (4), neoastilbin (5), 5-O-caffeoylquinic acid methyl ester (6), 3, 4-dihydroxybenzoic acid (7), isofraxidin (8).
Conclusion:
Compounds 1-6 were isolated from the genus Sarcandra for the first time. The glucuroide compounds compounds 1-3, were first isolated from the genus Sarcandra.
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