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The hyperekplexias and their relationship to the normal startle reflex
P Brown1, J C Rothwell, P D Thompson
1MRC Human Movement and Balance Unit, Institute of Neurology, London, UK.
Brain : a Journal of Neurology
|August 1, 1991
Summary
Patients with hyperekplexia exhibit abnormal startle responses, showing exaggerated motor reactions and resistance to habituation. These responses suggest a common brainstem pathway for both normal and pathological startle reflexes.
Area of Science:
- Neuroscience
- Neurology
- Human Physiology
Background:
- Hyperekplexia is a neurological disorder characterized by an exaggerated startle response.
- The neural mechanisms underlying the abnormal startle reflex in hyperekplexia are not fully understood.
- Previous research has identified abnormalities in reflex pathways but lacked detailed analysis of muscle recruitment patterns.