Jove
Visualize
Contact Us

Related Concept Videos

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification and characterization of a compound from Cuminum cyminum essential oil with antifibrilation and cytotoxic effect.

Research in pharmaceutical sciences·2015
Same author

Ultrastructural changes associated with myocardial apoptosis, in failing rat hearts induced by volume overload.

International journal of cardiology·2015
Same author

Chondrogenesis in co-culture: An intensive interaction between mesenchymal stem cells and primary chondrocytes.

Journal of stem cells & regenerative medicine·2014
Same author

Is tendinitis an inflammatory disease initiated and driven by pro-inflammatory cytokines such as interleukin 1β?

Histology and histopathology·2013
Same author

Anti-inflammatory and anti-catabolic effects of TENDOACTIVE® on human tenocytes in vitro.

Histology and histopathology·2011
Same author

Platelet-released growth factors can accelerate tenocyte proliferation and activate the anti-oxidant response element.

Histochemistry and cell biology·2011
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 29, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
11:22

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Mesenchymal stem cells as a potential pool for cartilage tissue engineering.

C Csaki1, P R A Schneider, M Shakibaei

  • 1Ludwig-Maximilians-University Munich, Faculty of Medicine, Institute of Anatomy, Musculoskeletal Research Group, Pettenkoferstrasse 11, D-80336 Munich, Germany. constanze.csaki@med.uni-muenchen.de

Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft
|October 10, 2008
PubMed
Summary

Mesenchymal stem cells (MSCs) show promise for repairing cartilage defects in osteoarthritis, offering an alternative to chondrocytes. Further research is needed to translate these findings from animal models to clinical applications for cartilage regeneration.

More Related Videos

Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells
12:10

Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: June 19, 2017

Implantation of Ferumoxides Labeled Human Mesenchymal Stem Cells in Cartilage Defects
04:39

Implantation of Ferumoxides Labeled Human Mesenchymal Stem Cells in Cartilage Defects

Published on: April 5, 2010

Related Experiment Videos

Last Updated: Jun 29, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
11:22

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells
12:10

Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: June 19, 2017

Implantation of Ferumoxides Labeled Human Mesenchymal Stem Cells in Cartilage Defects
04:39

Implantation of Ferumoxides Labeled Human Mesenchymal Stem Cells in Cartilage Defects

Published on: April 5, 2010

Area of Science:

  • Regenerative Medicine
  • Biomedical Engineering
  • Orthopedics

Background:

  • Osteoarthritis (OA) presents a significant clinical challenge due to articular cartilage's limited self-repair capacity.
  • Traditional treatments like Autologous Chondrocyte Transplantation face limitations including donor-site morbidity and cell de-differentiation.
  • Mesenchymal stem cells (MSCs) are emerging as a promising alternative cell source for cartilage repair.

Purpose of the Study:

  • To explore the potential of mesenchymal stem cells (MSCs) as an alternative to chondrocytes in cartilage tissue engineering.
  • To evaluate MSCs in combination with scaffolds and other regenerative medicine concepts for osteochondral defect repair.
  • To assess the current status and future directions of MSC-based therapies for cartilage regeneration.

Main Methods:

  • Review of current literature on cartilage repair strategies.
  • Analysis of studies investigating mesenchymal stem cells (MSCs) for osteochondral defect treatment.
  • Evaluation of preclinical data from animal models assessing MSC efficacy.

Main Results:

  • Mesenchymal stem cells (MSCs) demonstrate significant potential for cartilage repair in various animal models.
  • MSCs are being investigated as a cell source for novel implantable scaffolds and regenerative medicine approaches.
  • While promising, clinical translation of MSC-based cartilage repair strategies requires further investigation.

Conclusions:

  • Mesenchymal stem cells (MSCs) offer a viable alternative to chondrocytes for cartilage tissue engineering.
  • Further research and clinical trials are essential to establish the safety and efficacy of MSCs for treating osteoarthritis.
  • The development of MSC-based therapies holds significant promise for advancing the field of regenerative medicine in orthopedics.