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Related Concept Videos

Structural Joints: Fibrous Joints01:03

Structural Joints: Fibrous Joints

Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
Desmosomes01:05

Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Muscles of the Forearm that Move the Hand and Fingers01:16

Muscles of the Forearm that Move the Hand and Fingers

The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi radialis,...
Nondisjunction01:21

Nondisjunction

Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold sister...

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Related Experiment Video

Updated: Jun 29, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

[Syndactyly].

P Samson1, B Salazard

  • 1Institut de la main et du membre supérieur, clinique Monticelli, 88, rue du Commandant-Rolland, 13008 Marseille, France. philippe.samson@wanadoo.fr

Chirurgie De La Main
|October 10, 2008
PubMed
Summary
This summary is machine-generated.

Syndactyly, a common congenital hand anomaly, is surgically treated in infants. Surgical outcomes for syndactyly are generally excellent for simple cases but depend on underlying abnormalities in complex cases.

Related Experiment Videos

Last Updated: Jun 29, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Area of Science:

  • Orthopedics
  • Pediatric Surgery
  • Plastic Surgery

Background:

  • Syndactyly is a frequent congenital hand anomaly.
  • It can occur in isolation or as part of broader genetic syndromes.
  • Surgical intervention is typically recommended between 6 and 18 months of age.

Purpose of the Study:

  • To review the surgical management of syndactyly.
  • To discuss treatment strategies based on syndactyly type and severity.
  • To evaluate factors influencing functional and cosmetic outcomes.

Main Methods:

  • Surgical techniques including local flaps and direct closure for commissure construction.
  • Use of full-thickness skin grafts for complex or extensive syndactyly.
  • Assessment of outcomes based on case complexity and underlying abnormalities.

Main Results:

  • Simple syndactyly cases typically yield excellent functional and cosmetic results.
  • Local flaps and direct closure are effective for commissure construction.
  • Skin grafts are valuable for complex cases involving adjacent web spaces.

Conclusions:

  • Surgical correction of syndactyly can achieve excellent outcomes, particularly in simpler presentations.
  • Prognosis in complex syndactyly is significantly influenced by the degree of skeletal, articular, and tendinous involvement.
  • Timely surgical intervention is crucial for optimal hand function and aesthetics.