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Updated: Jun 29, 2026
06:38
An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Symptom management in hepatocellular carcinoma
Virginia Chih-Yi Sun1, Linda Sarna
1Department of Nursing Research and Education in Division of Population Sciences, City of Hope National Medical Center, Duarte, CA, USA. vsun@coh.org
Clinical Journal of Oncology Nursing
|October 10, 2008
Summary
Hepatocellular carcinoma (HCC) management focuses on controlling symptoms like pain and fatigue. Aggressive symptom control is vital for maintaining quality of life in HCC patients due to limited treatment options.
Area of Science:
- Hepatology
- Oncology
- Palliative Care
Background:
- Hepatocellular carcinoma (HCC) is a major cause of cancer death globally, with poor survival rates for unresectable cases.
- HCC disproportionately affects men and individuals of Asian descent, often linked to endemic viral hepatitis.
- Patients with HCC frequently experience multiple debilitating symptoms, including pain, fatigue, weight loss, and obstructive syndromes like ascites and jaundice.
Purpose of the Study:
- To provide an overview of the complex symptom management strategies for patients with Hepatocellular carcinoma (HCC).
- To emphasize the importance of aggressive symptom management in preserving physical functioning and quality of life for HCC patients.
Main Methods:
- This article provides a comprehensive overview based on existing literature and clinical practice guidelines.
- It highlights the common symptoms experienced by HCC patients and discusses management approaches.
Main Results:
- Multiple symptoms are common in HCC, significantly impacting patient well-being.
- Current treatment options for HCC have limitations, underscoring the need for effective symptom management.
Conclusions:
- Aggressive symptom management is crucial for improving the quality of life in patients with Hepatocellular carcinoma (HCC).
- A multidisciplinary team approach, with a key role for oncology nurses, is essential for optimal HCC symptom management.
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