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Updated: Jun 29, 2026

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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
Published on: September 19, 2022
Design and synthesis of intrinsically cell-penetrating nucleopeptides
Piero Geotti-Bianchini1, Julien Beyrath, Olivier Chaloin
1CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunologie et Chimie Thérapeutiques, 15 Rue René Descartes, 67000, Strasbourg, France.
Organic & Biomolecular Chemistry
|October 10, 2008
Abstract:
Nucleopeptides, which are constituted of alpha-amino acids bearing nucleobases at their side chains, are able to penetrate into cells and to reach the nucleus without cytotoxic effects.
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