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Nonrandom t(1;22)(p12-p13;q13) in acute megakaryocytic malignant proliferation
A Baruchel1, M T Daniel, G Schaison
1Service D'Hématologie Pédiatrique, Hôpital Saint-Louis, Paris, France.
Cancer Genetics and Cytogenetics
|July 15, 1991
Abstract:
A case of acute megakaryocytic leukemia (M7) and one of acute myeloid hemopathy affecting megakaryocytic and erythrocytic cell lineages in infants are reported. Both patients had t(1;22)(p12-p13;q13). This translocation was previously observed in a congenital M7 leukemia. These studies suggest that t(1;22) translocation can be nonrandom in M7.