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Related Concept Videos

Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...

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Related Experiment Video

Updated: Jun 29, 2026

Abdominal Massage to Improve Motor Dysfunction in Rats with Cerebral Palsy
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Abdominal Massage to Improve Motor Dysfunction in Rats with Cerebral Palsy

Published on: August 11, 2023

Acupuncture for restless legs syndrome.

Ye Cui1, Yin Wang, Zhishun Liu

  • 1Department of Acupuncture and Moxibustion, Guang An Men Hospital - China Academy of Chinese Medicine Science, No 5 Bei Xian Ge Street, Xuan Wu District, Beijing, China, 100053. cybnu@yahoo.com

The Cochrane Database of Systematic Reviews
|October 10, 2008
PubMed
Summary

This systematic review found insufficient evidence to confirm acupuncture

Area of Science:

  • Neurology
  • Integrative Medicine
  • Systematic Review

Background:

  • Restless legs syndrome (RLS) is a prevalent neurological movement disorder.
  • Patients with RLS often explore complementary therapies, including acupuncture.
  • The efficacy of acupuncture for RLS lacks comprehensive systematic evaluation.

Purpose of the Study:

  • To systematically evaluate the efficacy and safety of acupuncture for treating Restless Legs Syndrome (RLS).
  • To synthesize evidence from clinical trials comparing acupuncture with various control interventions for RLS.

Main Methods:

  • Comprehensive literature search across multiple databases (e.g., CENTRAL, MEDLINE, EMBASE, CBM, CNKI) up to February 2007.
  • Inclusion of randomized and quasi-randomized controlled trials comparing acupuncture to no intervention, placebo, sham acupuncture, pharmacological treatments, or other non-acupuncture interventions.

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Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture
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Published on: December 22, 2016

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Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture
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Published on: December 22, 2016

  • Independent data extraction and quality assessment by two authors; analysis using relative risk and weighted mean difference.

    • Main Results:

    • Only two trials involving 170 patients met the inclusion criteria; data could not be pooled due to clinical heterogeneity.
    • One trial showed no significant difference in overall symptom remission between acupuncture and medications.
    • A second trial indicated that dermal needle therapy combined with medications and massage improved leg sensations and RLS frequency compared to medications and massage alone, but not duration.

    Conclusions:

    • Current evidence is insufficient to establish acupuncture as an effective and safe treatment for Restless Legs Syndrome (RLS).
    • High-quality, large-scale randomized controlled trials are necessary to determine the true therapeutic value of acupuncture for RLS.