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Acupuncture and assisted conception.

Ying C Cheong1, Ernest Hung Yu Ng, William L Ledger

  • 1Obstetrics and Gynaecology, University of Southampton, Level F, Princess Anne Hospital, Coxford Road, Southampton, UK, SO16 5YA. yingcheong@hotmail.com

The Cochrane Database of Systematic Reviews
|October 10, 2008
PubMed
Summary
This summary is machine-generated.

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Acupuncture on embryo transfer day may improve live birth rates in assisted reproductive treatment (ART). However, more research is needed to confirm benefits and rule out placebo effects in infertility care.

Area of Science:

  • Reproductive Medicine
  • Integrative Oncology
  • Evidence-Based Medicine

Background:

  • Acupuncture is increasingly explored for assisted reproductive treatment (ART).
  • Its efficacy in reproductive medicine remains a subject of ongoing debate.
  • This review examines the current evidence on acupuncture's role in ART outcomes.

Purpose of the Study:

  • To systematically evaluate the effectiveness of acupuncture in improving ART outcomes.
  • To synthesize data from randomized controlled trials (RCTs) assessing acupuncture's impact on fertility treatments.

Main Methods:

  • A comprehensive search of multiple databases (e.g., CENTRAL, MEDLINE, EMBASE) was conducted for RCTs up to August 2007.
  • Included studies involved acupuncture for couples undergoing ART, comparing it against no treatment, placebo, or sham acupuncture.

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  • Meta-analysis of 13 RCTs assessed live birth rate, pregnancy rate, miscarriage rate, and side effects.

    • Main Results:

    • Acupuncture administered on the day of embryo transfer (ET) demonstrated a significant benefit for live birth rate (OR 1.89).
    • Acupuncture performed two to three days post-ET did not show a significant benefit (OR 1.79).
    • No evidence of benefit was found for acupuncture around the time of oocyte retrieval.

    Conclusions:

    • Acupuncture on ET day shows a potential benefit for live birth rates in ART.
    • The observed effect may be influenced by placebo and limited trial sample sizes.
    • Further high-quality, adequately powered RCTs are necessary before recommending acupuncture during the luteal phase in routine practice.