[Antibacterial therapy of patients with complicated diabetic foot]

The main reason for hospitalization and lethality of patients with diabetes mellitus are the infectious complications of the lower limbs. In the period 2000-2005, 147 were treated for complications with the diabetic foot in the Surgical Clinic at the Ministry of Interior Medical Institute. 105 of them were men and 42 - women. The average age of the patients was 67 +/- 8.2. Different number of microorganisms, from 2 to 8, was identified in testing the material from the wound secret. Mixed (anaerobic-aerobic) infection was found in 135 patients (91.8%), and only aerobic infection - in 12 patients (8.2%). Staphylococcus aureus (61%) and Staphylococcus epidermidis (21%) were the most often found ones from the facultative-anaerobic microorganisms in the associations. Bacteroides fragilis (23%), Peptococcus spp. (19%) and Fusobacterium spp. (11%) were the most often found ones from the sporogenic anaerobic microorganisms. The empirical and etiotropic antibacterial therapy, the different combinations of antibacterial preparations and the results of their application were discussed.