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Updated: Jun 29, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
[Analysis of microbial flora during operation for cholangitis and other inflammatory deseases of the hepato-billiary
Background:
Inflammatory deseases of the billiary system are common in the hepato-billiary surgery. Most serious is the cholangitis. Treatment is based on individual approach of choice of moment of correct surgical intervention and corresponding adequate antibiotic therapy.
Aim:
Retrospective analysis of the experience of our clinic of the positive biliocultures and their antibiograms.
Materials And Methods:
152 positive biliocultures taken intraoperativly, for 10 years period. 48 of them are from patients with cholangitis.
Results:
Analysis of count and species microbiological agents and their sensitivity to antibiogram antibiotics in table format. The data of the literature reviewed and discussed.
Conclusions:
Most common microbiological agents are E. coli 60%, Klebsiella 31%, Pseudomonas 24%. In 40% theres are more then one agent. Most common agents have big sensivity to Cefalosporines II-III generation, Amikacin, Ciprofloxacin and Carbapenems.
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