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Updated: Jun 29, 2026
Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model
Published on: August 11, 2023
[Variance of serum prolactin in controlled ovarian stimulation]
Xiao-Yan Liang1, Yong-Lao Xiong, Guang-Lun Zhuang
1Department of Assisted Reproductive Technology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. lxyzy@263.net
Objective:
To investigate the variance of peripheral blood prolactin (PRL) in controlled ovarian stimulation.
Methods:
Seventy-two patients, with totally 106 cycles receiving a long protocol of gonadotropin-releasing hormone agonist combined with gonadotropin (Gn) were randomly enrolled in this retrospective study. During controlled ovarian stimulation, peripheral blood hormones were measured by chemiluminescent microparticle immunoassay.
Results:
Prolactin was positively correlated with estradiol (r = 0.5897, P < 0.01) while there was no significant correlation between luteinizing hormone and PRL Progesterone had a positive relation with prolactin (r = 0.1412, P < 0.01).
Conclusions:
During controlled ovarian stimulation, prolactin secretion is not affected by Gn but may be stimulated by estradiol. Progesterone has a positive relation with prolactin.
