Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization of Andrographolide Nanocrystal-loaded Liposomes by Box-Behnken Design and its <i>In vitro</i> and <i>In vivo</i> Evaluation.

Current drug delivery·2026
Same author

Approaches for enhancing bioavailability of macromolecular drugs.

International journal of pharmaceutics·2026
Same author

Dependence of the Extra-Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter.

Magnetic resonance in medicine·2026
Same author

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell-platelet-endothelial cell interactions.

Oncology letters·2026
Same author

Mechanisms influencing adult children's willingness to use medical visit accompaniment services for older adults in Nanjing: a structural equation modeling study.

Frontiers in public health·2026
Same author

High-fidelity compressed high-speed imaging for resolving rapid micro-dynamics.

Optics express·2026
Same journal

Higher-Order Clustering of Receptors Real-Time Projected by Plasmon-ruler on the Single Live Cell.

Nano letters·2026
Same journal

Achieving Fermi-Level Depinning and Ideal Metal Contact in <i>β</i>-Ga<sub>2</sub>O<sub>3</sub> Devices via MXene Integration.

Nano letters·2026
Same journal

AI-Assisted Electron Microscopy in Structure-Performance Analysis of Advanced Catalysts: From Atomic Resolution to Statistical Significance.

Nano letters·2026
Same journal

Electrically Switchable Ultraslow Dispersionless Polaritons via Twist Engineering in van der Waals Heterostructures.

Nano letters·2026
Same journal

Correction to "Ultrasonication-Triggered Ubiquitous Assembly of Magnetic Janus Amphiphilic Nanoparticles in Cancer Theranostic Applications".

Nano letters·2026
Same journal

Tunable Proximity Valley Splitting Via Interfacial Exchange Pinning in WSe<sub>2</sub>-CrBr<sub>3</sub>-CrPS<sub>4</sub> Heterostructures.

Nano letters·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2026

Observation and Analysis of Blinking Surface-enhanced Raman Scattering
05:52

Observation and Analysis of Blinking Surface-enhanced Raman Scattering

Published on: January 11, 2018

Blinking statistics correlated with nanoparticle number.

Siying Wang1, Claudia Querner, Michael D Fischbein

  • 1Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Nano Letters
|October 11, 2008
PubMed
Summary
This summary is machine-generated.

Single semiconductor nanorods (NRs) and small clusters exhibit distinct fluorescence blinking patterns. Blinking statistics reveal differences in clusters of five or more NRs compared to individual NRs.

More Related Videos

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
08:51

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry

Published on: March 1, 2013

Improving Reproducibility to Meet Minimal Information for Studies of Extracellular Vesicles 2018 Guidelines in Nanoparticle Tracking Analysis
08:52

Improving Reproducibility to Meet Minimal Information for Studies of Extracellular Vesicles 2018 Guidelines in Nanoparticle Tracking Analysis

Published on: November 17, 2021

Related Experiment Videos

Last Updated: Jun 29, 2026

Observation and Analysis of Blinking Surface-enhanced Raman Scattering
05:52

Observation and Analysis of Blinking Surface-enhanced Raman Scattering

Published on: January 11, 2018

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
08:51

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry

Published on: March 1, 2013

Improving Reproducibility to Meet Minimal Information for Studies of Extracellular Vesicles 2018 Guidelines in Nanoparticle Tracking Analysis
08:52

Improving Reproducibility to Meet Minimal Information for Studies of Extracellular Vesicles 2018 Guidelines in Nanoparticle Tracking Analysis

Published on: November 17, 2021

Area of Science:

  • Materials Science
  • Nanotechnology
  • Physical Chemistry

Background:

  • Semiconductor nanorods (NRs) are crucial in optoelectronic applications.
  • Understanding single NR and few-NR cluster fluorescence is key to controlling their properties.
  • Blinking statistics provide insights into nanoparticle dynamics and surface states.

Purpose of the Study:

  • To correlate single NR and few-NR cluster fluorescence with their exact particle number.
  • To investigate how the number of NRs in a cluster affects fluorescence blinking behavior.
  • To analyze the statistical parameters of fluorescence intermittency in individual NRs and small clusters.

Main Methods:

  • Correlating fluorescence microscopy of single NRs and few-NR clusters with transmission electron microscopy (TEM).
  • Analyzing fluorescence intensity trajectories, I(t), over extended periods (2.4 x 10^4 s).
  • Calculating and comparing on- and off-time probability densities and truncation times.

Main Results:

  • Approximately 75% of observed blinking sources were individual NRs, with the rest being small clusters (up to 15 NRs).
  • Two- and three-NR clusters showed fluorescence blinking statistics indistinguishable from individual NRs.
  • Clusters of five or more NRs exhibited statistically distinguishable blinking parameters, with 'truncation time' increasing superlinearly with particle number.
  • Observed truncation of the power law distribution of off-times for single nanoparticles.

Conclusions:

  • The number of NRs in a cluster significantly influences fluorescence blinking behavior, especially for clusters of five or more.
  • Blinking statistics can serve as a sensitive probe for distinguishing individual NRs from small clusters.
  • The study provides new insights into nanoparticle dynamics and reveals previously unobserved blinking characteristics for single NRs.