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Updated: Jun 29, 2026
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Efficacy of a day-care program in the treatment of psoriasis
Junling Zhang1, David N Adam, Elaine Stebbing
1Psoriasis and Phototherapy Clinic, Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC.
Background:
Few data exist documenting the effectiveness of psoriasis day-care treatment programs (PDTPs) using standardized efficacy measurements.
Objectives:
We sought to analyze the efficacy of a PDTP using the Psoriasis Area and Severity Index (PASI).
Methods:
A retrospective review was performed on 132 patients treated at our PDTP. Sufficient data existed to permit PASI analysis using a simplified method for a representative subgroup of 64 patients, who formed the study population. Patients received phototherapy and topical treatments over 2 weeks. The outcome measures included a baseline and day 11 PASI, a physician global assessment (PGA), and adverse events reported by the patients.
Results:
Mean baseline PASI was 13.6 (N = 64), with a 59.6% reduction by day 11. A PASI reduction of > or = 50% was seen in 75% of patients, with 30% of patients achieving > or = 75% reduction of PASI. Day 11 PGA demonstrated a 69.9% improvement.
Conclusion:
With a reduction in PASI of 59.6% at 11 days, our PDTP, with phototherapy and topical agents, seems to be a rapid and effective therapy for psoriasis.
