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Related Experiment Video

Updated: Jun 29, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

[Indication for haemoderivatives in dengue].

Investigacion Clinica

|October 14, 2008

Summary

Careful management of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) focuses on fluid replacement. Preventive blood transfusions are not beneficial and may increase hospitalization and risks.

Area of Science:

Critical care medicine
Infectious diseases
Hematology

Background:

Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) management necessitates specialized care.
Treatment relies on physiological replacement therapy and meticulous fluid control.

Discussion:

Blood product transfusion criteria are specific, particularly during disseminated intravascular coagulation (DIC) in the hemorrhagic phase.
Close monitoring of bleeding manifestations and laboratory parameters is essential.

Key Insights:

Preventive transfusion offers no advantages in treating DHF/DSS.
Prophylactic transfusions are associated with increased hospitalization duration and pulmonary edema development.

Outlook:

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Further research into optimal transfusion triggers during DHF/DSS is warranted.
Focus on evidence-based fluid management and risk mitigation strategies for transfusion-related complications.