Related Experiment Video
Updated: Jun 29, 2026

13:55
Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
Castlemans disease in HIV infected patient from eastern India
D Modak1, R R Ganguly, S N Haldar
1Department of Tropical Medicine, School of Tropical Medicine, Kolkata.
The Journal of the Association of Physicians of India
|October 14, 2008
Summary
Castlemans disease, a rare lymphoproliferative disorder, was observed in a patient with advanced HIV infection. Effective treatment with highly active antiretroviral therapy (HAART) was noted, highlighting a positive outcome in Eastern India.
Area of Science:
- Hematology
- Infectious Diseases
- Oncology
Background:
- Castlemans disease is a rare lymphoproliferative disorder with diverse clinical presentations.
- Advanced Human Immunodeficiency Virus (HIV) infection can complicate the management of lymphoproliferative disorders.
- The eastern region of India has limited reported cases of Castlemans disease.
Observation:
- A case of Castlemans disease in a patient with advanced HIV infection is presented.
- The patient was treated with conventional highly active antiretroviral therapy (HAART).
Findings:
- The patient exhibited a favorable response to standard HAART.
- This case demonstrates a positive outcome for Castlemans disease in the context of advanced HIV infection.
Implications:
- This case suggests that HAART may be an effective treatment strategy for Castlemans disease in patients with advanced HIV.
- The findings contribute to understanding the management of rare lymphoproliferative disorders in co-infected individuals.
- Further research is warranted to explore the efficacy of antiretroviral therapy in managing Castlemans disease in HIV-positive populations, particularly in underrepresented geographic regions.
Related Concept Videos
Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Immunodeficiency Diseases
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
There are three main causes of immunodeficiency disorders...