Related Experiment Video
Updated: Jul 30, 2026

10:57
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Equine helminth infections: control by selective chemotherapy
1Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
Equine Veterinary Journal
|May 1, 1991
Summary
Selective deworming in horses using fecal egg counts (FEC) showed initial success but parasite levels rebounded. Early FEC predicted future needs, suggesting targeted treatment for high-shedding horses in strategic anthelmintic programs.
Area of Science:
- Veterinary Parasitology
- Equine Health Management
- Anthelmintic Resistance
Background:
- Internal parasite control in horses is crucial for herd health.
- Selective anthelmintic therapy aims to reduce drug resistance and treatment costs.
- Monitoring fecal egg counts (FEC) is a key component of parasite management.
Purpose of the Study:
- To evaluate the effectiveness of a selective anthelmintic therapy program in a horse herd.
- To determine if initial fecal egg counts predict future parasite shedding and treatment needs.
- To assess the long-term efficacy of selective deworming strategies.
Main Methods:
- A herd of 31 horses underwent selective anthelmintic therapy over a year.
- Fecal egg counts (FEC) were performed bimonthly.
- Horses with FEC ≥ 100 eggs per gram (epg) received ivermectin; others were untreated.
- Herd median FEC ≤ 100 epg was the criterion for adequate control.
Main Results:
- Selective therapy initially achieved adequate control (median herd FEC 0 epg after nine months).
- Parasite levels rebounded after horses returned to pasture (median herd FEC 325 epg).
- Initial September FEC significantly correlated with the following September's FEC and predicted treatment frequency.
- Horse age did not correlate with treatment requirements.
Conclusions:
- Selective anthelmintic therapy can be effective in the short term but requires ongoing monitoring.
- Initial fecal egg counts are valuable predictors for targeted deworming strategies in horses.
- Incorporating FEC into strategic anthelmintic programs can economically identify and manage high-shedding horses.
Related Concept Videos
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
Anthelminthic Agents
Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
Antiprotozoal Agents
Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...

