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Ischemic stroke as the presenting symptom of primary hyperparathyroidism due to multiple endocrine neoplasia type 1

Naim Mitre1, Kenneth Mack, Dusica Babovic-Vuksanovic

  • 1Division of Pediatric Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

The Journal of Pediatrics
|October 14, 2008
PubMed

Insights

Primary hyperparathyroidism can cause ischemic stroke in children, even without high blood pressure. Doctors should test calcium and parathyroid hormone levels in children experiencing stroke symptoms.

Area of Science:

  • Pediatric Neurology
  • Endocrinology
  • Cardiovascular Research

Background:

  • Primary hyperparathyroidism is a rare endocrine disorder.
  • Cerebrovascular events in children are uncommon and require thorough investigation.

Observation:

  • A 14-year-old male presented with an ischemic stroke.
  • The patient had primary hyperparathyroidism without a history of hypertension.

Findings:

  • This case highlights a potential link between primary hyperparathyroidism and stroke in pediatric patients.
  • Serum calcium and parathyroid hormone levels may serve as crucial diagnostic markers.

Implications:

  • Routine screening for hyperparathyroidism is recommended for children with stroke.
  • Early diagnosis and management of primary hyperparathyroidism can prevent severe neurological complications.

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