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Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Related Experiment Video

Updated: Jun 29, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Combined imaging modalities: PET/CT and SPECT/CT.

Alan H Maurer1

  • 1Temple University School of Medicine, Philadelphia, PA 19140, USA. amaurer@temple.edu

Health Physics
|October 14, 2008
PubMed
Summary

New radiopharmaceuticals enable cellular-level molecular imaging for improved disease diagnosis and treatment. Fused PET/CT and SPECT/CT systems combine functional and anatomical data, particularly valuable in oncology.

Area of Science:

  • Medical Imaging
  • Radiopharmaceuticals
  • Molecular Biology

Background:

  • Advancements in radiopharmaceuticals facilitate molecular imaging at the cellular level.
  • Fused PET/CT and SPECT/CT systems integrate metabolic/functional data with high-resolution CT anatomy.
  • This fusion aids in mapping metabolic activity to anatomical structures for disease assessment.

Purpose of the Study:

  • To highlight the clinical value of fused PET/CT and SPECT/CT imaging.
  • To discuss the applications of molecular imaging in oncology, cardiology, neurology, and infection imaging.
  • To outline future directions in integrated imaging instrumentation and novel radiopharmaceuticals.

Main Methods:

  • Utilizing fused Positron Emission Tomography/Computed Tomography (PET/CT) and Single-Photon Emission Computed Tomography/CT (SPECT/CT) imaging systems.

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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  • Employing F-18 fluorodeoxyglucose (FDG) as a common PET imaging agent.
  • Combining functional and anatomical imaging data for comprehensive patient assessment.

    • Main Results:

    • Fused imaging demonstrates significant clinical value, especially in oncology.
    • FDG uptake, while nonspecific, shows important applications in cancer patients.
    • Growing indications for fused imaging in cardiology, neurology, and infection imaging are emerging.

    Conclusions:

    • Fused anatomic and molecular imaging significantly improves disease diagnosis and treatment.
    • Continued advancements in integrated imaging technology and targeted radiopharmaceuticals are expected.
    • Molecular imaging holds promise for more specific visualization of organ and cell biology.