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Related Experiment Video

Updated: Jun 29, 2026

A Modified Method for Intrathecal Catheterization in Rats
11:15

A Modified Method for Intrathecal Catheterization in Rats

Published on: February 14, 2025

Subdural intrathecal catheter placement: experience with two cases.

Andrea Sorokin1, Emil Annabi, Wen-Chang Yang

  • 1Montefiore Medical Center, Department of Anesthesiology, Bronx, NY 10467, USA. andrea.sorokin@mssm.edu

Pain Physician
|October 14, 2008
PubMed
Summary

Subdural placement of intrathecal catheters, though rare, can occur during initial implantation. This can lead to delayed detection of drug delivery issues and requires consideration in pump malfunction diagnostics.

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Area of Science:

  • Neurosurgery
  • Neurology
  • Pain Management

Background:

  • Subdural migration of epidural catheters is a recognized complication.
  • Subdural placement of intrathecal catheters has not been previously documented.
  • This study presents two cases of subdural placement of intrathecal catheters.

Observation:

  • Case 1: Intrathecal baclofen catheter migrated subdural, causing drug sequestration and inadequate pain relief.
  • Case 2: Intrathecal pain pump catheter initially placed subdural, requiring surgical revision for proper cerebrospinal fluid (CSF) delivery.
  • Both cases highlight delayed diagnosis of catheter malpositioning.

Findings:

  • Intrathecal catheters can enter the subdural space during initial implantation.
  • Subdural catheter placement may not be immediately apparent and can lead to prolonged periods of undetected malfunction.

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Last Updated: Jun 29, 2026

A Modified Method for Intrathecal Catheterization in Rats
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Published on: February 14, 2025

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Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System

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  • Tissue encapsulation of the catheter tip can impede direct CSF communication.

    • Implications:

    • Subdural placement of intrathecal catheters should be considered in the differential diagnosis of malfunctioning drug infusion pumps.
    • Early imaging and diagnosis are crucial for effective management of intrathecal catheter complications.
    • This finding expands the understanding of intrathecal catheter-related adverse events.