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Related Concept Videos

Somatosensation01:33

Somatosensation

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The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Disorders of the Autonomic Nervous System01:18

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
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Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
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In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
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Related Experiment Video

Updated: Jan 19, 2026

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
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Phantom sweating: a novel autonomic paresthesia.

Lindsey Lair1, Christopher Gibbons, Roy Freeman

  • 1Autonomic and Peripheral Nerve Laboratory, Dept. of Neurology, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02215, USA.

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
|October 14, 2008
PubMed
Summary

Phantom sweating, a new autonomic neuropathy symptom, was observed in a patient with small fiber neuropathy. This autonomic paresthesia may occur frequently after sympathectomy.

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Area of Science:

  • Neurology
  • Autonomic Nervous System Disorders
  • Clinical Neuroscience

Background:

  • Autonomic neuropathy is a complex neurological disorder affecting involuntary bodily functions.
  • Phantom sweating is a poorly understood symptom with limited research.
  • Small fiber neuropathy impacts unmyelinated nerve fibers, leading to various sensory and autonomic disturbances.

Observation:

  • A patient presenting with generalized small fiber and autonomic neuropathy was studied.
  • Clinical and laboratory assessments were conducted to evaluate the neuropathy.
  • The patient exhibited symptoms indicative of phantom sweating.

Findings:

  • The study identified evidence of a generalized small fiber and autonomic neuropathy.
  • Phantom sweating was noted in the context of this neuropathy.
  • This symptom has not been previously reported in patients with somatosensory or autonomic neuropathy.

Implications:

  • The findings suggest phantom sweating could be a manifestation of autonomic paresthesia.
  • This research expands the understanding of autonomic neuropathy symptoms.
  • Further investigation into phantom sweating may reveal new diagnostic or therapeutic targets for autonomic dysfunction.