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Updated: Jun 29, 2026

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Published on: June 12, 2021
Time-resolved spectra of single-bubble sonoluminescence in sulfuric acid with a streak camera
Weizhong Chen1, Wei Huang, Yue Liang
1The Key Laboratory of Modern Acoustics, Ministry of Education, and Institute of Acoustics, Nanjing University, Nanjing 210093, China. wzchen@nju.edu.cn
Abstract:
The time-resolved spectra of single-bubble sonoluminescence (SBSL) in sulfuric acid have been observed with a streak camera after a spectrograph. The spectral center evolves from infrared to ultraviolet gradually within a SBSL duration, which corresponds to an increase of temperature. The peak temperature within one sonoluminescence (SL) duration is 5-9 times higher than the average temperature based on the average spectrum in our experiment. Furthermore, the ratio of the peak temperature to average temperature increases with the increase of driving pressure. The SBSL flash dies out after a dramatic heating-up, and there is no cooling procedure observed at the time resolution of 110 SL duration, which is incompatible with the radius-related adiabatic heating model as the mechanism of SBSL.

