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Related Experiment Video

Updated: Jun 29, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Refractive change following pseudophakic vitrectomy.

Sinead Byrne1, James Ng, Anthony Hildreth

  • 1Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland, Tyne and Wear, UK. sineadambyrne@hotmail.com

BMC Ophthalmology
|October 15, 2008
PubMed
Summary

Pseudophakic eyes undergoing vitrectomy experienced significant refractive changes, with most showing a myopic shift. The exact cause of this refractive change remains unclear.

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Last Updated: Jun 29, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Refractive Error

Background:

  • Pseudophakic eyes undergoing pars plana vitrectomy without scleral buckling can experience refractive changes.
  • Understanding these changes and their causes is crucial for patient outcomes.

Purpose of the Study:

  • To assess the occurrence and magnitude of refractive change in pseudophakic eyes after 20-gauge pars plana vitrectomy.
  • To investigate potential etiological factors contributing to refractive shifts.

Main Methods:

  • Retrospective review of 87 pseudophakic eyes that underwent 20-gauge pars plana vitrectomy.
  • Measurement of anterior chamber depth (ACD) before and after surgery in 32 eyes.
  • Comparison with 43 pseudophakic fellow eyes as controls.

Main Results:

  • A statistically significant mean myopic shift of -0.45 diopters was observed post-vitrectomy (p < 0.001).
  • 70% of eyes (61/87) showed a myopic shift, with 52% (45/87) shifting by -0.5 diopters or more.
  • No significant changes in anterior chamber depth or associations with other pre-, intra-, or postoperative factors were found.

Conclusions:

  • Significant refractive changes, primarily a myopic shift, occur in some pseudophakic patients post-vitrectomy.
  • While the mean shift is small, the range of change is considerable.
  • The etiology of the observed refractive changes remains uncertain.