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A simple hepatic cyst with elevated serum and cyst fluid CA19-9 levels: a case report

Hidekatsu Yanai1, Norio Tada

  • 1Department of Internal Medicine, Division of General Medicine, Kashiwa Hospital, The Jikei University School of Medicine, Kashiwashita, Kashiwa, Chiba, Japan. yanaih@jikei.ac.jp

Journal of Medical Case Reports
|October 15, 2008
PubMed

Insights

This study investigated how minocycline hydrochloride instillation affects CA19-9 levels in a patient with a simple hepatic cyst. Treatment led to decreased serum CA19-9 and increased cyst fluid CA19-9 levels.

Area of Science:

  • Hepatology
  • Gastroenterology
  • Medical Case Study

Background:

  • Simple hepatic cysts are usually asymptomatic but can cause symptoms when large or complicated.
  • Elevated CA19-9 levels can occur in hepatic cysts, mimicking other conditions.
  • This case examines a patient with an infected hepatic cyst and high CA19-9.

Purpose of the Study:

  • To report the first case of intracystic minocycline hydrochloride instillation in a patient with a simple hepatic cyst.
  • To analyze the impact of this treatment on serum and cyst fluid CA19-9 levels.

Main Methods:

  • A 76-year-old woman with an infected hepatic cyst underwent treatment.
  • Minocycline hydrochloride was instilled into the cyst.
  • Serum and cyst fluid CA19-9 levels were measured before and after treatment.

Main Results:

  • The hepatic cyst collapsed within one week after treatment.
  • Serum CA19-9 levels significantly decreased post-treatment.
  • Cyst fluid CA19-9 levels remarkably increased after minocycline hydrochloride instillation.

Conclusions:

  • Intracystic minocycline hydrochloride instillation can effectively treat infected hepatic cysts.
  • The treatment influences serum and cyst fluid CA19-9 levels in a distinct manner.
  • This is the first report detailing these specific CA19-9 level changes.
Abstract

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