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Updated: Jun 29, 2026

Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Salvage of a congested DIEAP flap with subcutaneous recombinant tissue plasminogen activator treatment
Suhan Ayhan1, Safak Uygur, Ismail Kucukoduk
1Gazi University, Faculty of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Ankara, Turkey. msayhan@gazi.edu.tr
Abstract:
Thrombolytic agents are frequently employed in the treatment of thrombosis in combination with early surgical exploration and management. Recombinant tissue plasminogen activator is a second generation thrombolytic agent, which acts specifically at the site of the haemostatic clot with minimal side effects. In this paper, we present a case with venous congestion of the deep inferior epigastric artery perforator (DIEAP) flap, despite a patent anastomosis, in which we achieved a successful outcome with subcutaneous recombinant tissue plasminogen activator treatment.