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Kidney transplantation from elderly living donors
M Haberal1, S Sert, S Altunkan
1Turkish Transplantation and Burn Foundation Hospital, Ankara.
The International Journal of Artificial Organs
|June 1, 1991
Summary
Elderly living donors aged 60 and older can provide satisfactory kidneys for transplantation. This approach, using donor-specific transfusions and low-dose triple therapy, shows promising patient and graft survival rates.
Area of Science:
- Nephrology
- Transplantation Surgery
- Geriatric Medicine
Background:
- Critical shortage of organs for kidney transplantation necessitates exploring alternative donor sources.
- Increasing acceptance of organ donation from elderly individuals globally.
- Previous concerns regarding the viability and outcomes of organs from older donors.
Purpose of the Study:
- To evaluate the efficacy and safety of using kidneys from elderly living related donors (≥60 years) for transplantation.
- To assess patient and graft survival rates in recipients of elderly donor kidneys.
- To determine the suitability of low-dose triple immunosuppressive therapy in this donor population.
Main Methods:
- Conducted 34 kidney transplantations using living related donors aged 60 years and older.
- Administered donor-specific transfusions to all recipients prior to transplantation.
- Utilized a low-dose triple immunosuppressive drug regimen for all recipients post-transplantation.
Main Results:
- Achieved an overall patient survival rate of 97.5%.
- Recorded a graft survival rate of 85.29% in the study cohort.
- Demonstrated successful transplantation outcomes with elderly donor kidneys.
Conclusions:
- Kidneys from elderly living donors (≥60 years) can be transplanted successfully.
- Low-dose triple therapy is an effective immunosuppressive strategy for recipients of elderly donor kidneys.
- Utilizing elderly living donors is a viable strategy to address organ shortages in kidney transplantation.