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Updated: Jun 29, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Combat ocular trauma and systemic injury.

Eric D Weichel1, Marcus H Colyer

  • 1Walter Reed Army Medical Center, Washington, District of Columbia 20307, USA. eweichel@hotmail.com

Current Opinion in Ophthalmology
|October 16, 2008
PubMed
Summary
This summary is machine-generated.

Combat eye injuries from modern warfare, often caused by blast injuries, lead to severe vision loss. Early management strategies are crucial for improving outcomes in these complex cases.

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Area of Science:

  • Ophthalmology
  • Military Medicine
  • Trauma Surgery

Background:

  • Combat ocular trauma presents unique challenges in modern warfare.
  • Operations Iraqi Freedom and Enduring Freedom have provided insights into the nature of these injuries.

Purpose of the Study:

  • Review recent literature on combat ocular trauma.
  • Classify combat-related eye injuries.
  • Propose management strategies for eye injuries sustained in conflict.

Main Methods:

  • Literature review of combat ocular trauma from recent military operations.
  • Analysis of injury patterns, causes, and outcomes.
  • Discussion of classification systems and management approaches.

Main Results:

  • Unconventional fragmentary munitions are the primary cause of combat ocular injuries, often resulting in blast trauma.
  • High rates of concomitant injuries, including traumatic brain injury and amputations, are observed.
  • Open-globe and adnexal lacerations are frequent; severe globe injuries lead to high rates of enucleation and retained intraocular foreign bodies.
  • Delayed removal of intraocular foreign bodies did not impact visual outcomes or lead to endophthalmitis.
  • Significant vision loss persists in perforating globe injuries and posterior segment trauma.

Conclusions:

  • Recent literature highlights the severity of ocular and systemic injuries from Operations Iraqi and Enduring Freedom.
  • Classification and understanding of outcome measures are essential for managing combat eye trauma.
  • Despite advances, severe vision loss remains a challenge in complex combat-related eye injuries.