Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in
1Department of Pulmonary Medicine, University of Colorado Health Sciences Center, Denver, CO, USA.
Neurogenetics
|October 16, 2008
Abstract:
We performed a prospective analysis on 14 11q- patients to determine the relationship between the degree of cognitive impairment and relative deletion size. Seventeen measures of cognitive function were assessed. All nine patients with a deletion of at least 12.1 Mb had severe global cognitive impairment, with full-scale IQ <50, whereas all five patients with smaller deletions,
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