Related Experiment Video
Updated: Jun 29, 2026

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
Published on: November 7, 2019
Novel visualization of intracardiac pacing lead extractions: methodologies performed within isolated canine hearts
Charles J Love1, Sarah E Ahlberg, Prasanga Hiniduma-Lokuge
1Division of Cardiovascular Medicine, Ohio State University, 200 DAV HT&LNG, 473 W. 12th Ave., Columbus, OH 43210, USA.
Abstract:
Several methodologies are typically employed to extract chronically-implanted pacing leads including: laser catheter systems, radio frequency catheters, mechanical cutting catheters, and/or direct traction. In the present study, Visible Heart(R) methodologies were employed to obtain novel internal and external views of such extractions. Utilizing standard cardioplegia procedures, canine hearts (n = 3) with chronically-implanted endocardial pacing leads were explanted to a unique isolated heart apparatus. Modified Krebs-Henseleit buffer allowed for clear endocardial imaging with endoscopic video cameras inserted into the cardiac chambers. Leads were extracted using: (1) laser system with sheath; (2) dissection sheath with incorporated bipolar tungsten electrode; (3) non-powered mechanical sheath; or (4) direct traction. Resultant images provide a novel perspective regarding lead extraction methodologies and the imposed force on an encapsulated lead and on the great vessels and/or heart itself; this understanding may improve the outcome and safety of future lead extractions.

