Related Experiment Video
Updated: Jun 29, 2026

07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
A simplified direct endonasal approach for transsphenoidal surgery.
M Nejadkazem1, A Samii, R Fahlbusch
1Department of Ear, Nose and Throat, Imam Reza University Hospital, Tabriz, Iran.
Minimally Invasive Neurosurgery : MIN
|October 16, 2008
Summary
The direct endonasal approach for hypophysectomy offers a minimally invasive technique, reducing complications and enhancing patient comfort. This method provides superior visualization and more effective lesion removal compared to traditional intracranial or transseptal routes.
Area of Science:
- Neurosurgery
- Endoscopic Surgery
- Pituitary Surgery
Background:
- The senior author has extensive experience with over 4,000 hypophysectomy operations.
- Surgical approaches have evolved from intracranial and transseptal to the direct endonasal technique.
Purpose of the Study:
- To introduce the direct endonasal approach as a minimally invasive technique for hypophysectomy.
- To highlight the benefits of this approach in reducing complications and improving patient comfort.
Main Methods:
- The direct endonasal approach is utilized as a minimal access technique.
- This method provides a direct route to the sella turcica, avoiding brain retraction.
Main Results:
- The endonasal approach offers excellent visualization of the pituitary gland and related lesions.
- It enables more effective lesion removal and superior clinical outcomes.
- Complication rates are reduced with this technique.
Conclusions:
- The direct endonasal approach is the least traumatic route to the sella turcica.
- Endoscopic visualization enhances surgical effectiveness and patient results.
- This technique represents an advancement in pituitary surgery.
