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Related Experiment Video

Updated: Jun 29, 2026

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

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Published on: August 10, 2014

Nicotine self-medication of cognitive-attentional processing.

David E Evans¹, David J Drobes

¹Moffitt Cancer Center, Tampa, FL 33617, USA.

Addiction Biology

|October 16, 2008

Summary

Nicotine

Area of Science:

Neuroscience
Psychology

Background:

Nicotine's impact on cognitive function is complex.
Research often focuses on withdrawal symptom alleviation.
Direct cognitive enhancement by nicotine is debated.

Purpose of the Study:

Review nicotine's cognitive effects.
Explore neurobiological mechanisms.
Examine factors influencing these effects and their significance in smokers with cognitive deficits.

Main Methods:

Selective review of existing research.
Analysis of neurobiological mechanisms.
Discussion of task and experimental features.

Main Results:

Nicotine affects various cognitive processes.

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Published on: February 10, 2012

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The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

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Spectral Confocal Imaging of Fluorescently tagged Nicotinic Receptors in Knock-in Mice with Chronic Nicotine Administration

Spectral Confocal Imaging of Fluorescently tagged Nicotinic Receptors in Knock-in Mice with Chronic Nicotine Administration

Published on: February 10, 2012

Cognitive self-medication may explain some effects.

Effects are amplified in smokers with cognitive deficits.

Conclusions:

Further theory-driven research on nicotine's cognitive effects is needed.
Develop targeted smoking cessation programs.
Understand cognitive self-medication in high-risk individuals.