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MAP3Ks as central regulators of cell fate during development

Evisabel A Craig1, Mark V Stevens, Richard R Vaillancourt

  • 1Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.

Developmental Dynamics : an Official Publication of the American Association of Anatomists
|October 16, 2008
PubMed
Summary

Mitogen-activated protein (MAP) kinase kinase kinase (MAP3K) pathways regulate cellular responses. This review details MAP3K signaling routes and mouse models, revealing context-dependent functions and potential redundancy in developmental biology.

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