Related Experiment Videos
Synthesis and antifungal activity of some new benzimidazole derivatives
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ankara, Turkey.
Archiv Der Pharmazie
|May 1, 1991
Abstract:
Synthesis and antifungal evaluation of 5-ethoxycarbonyl-2-(substituted-benzyl or phenoxymethyl)benzimidazoles are reported. Structures of the compounds were elucidated with IR-, 1H-NMR-, 13C-NMR-, mass-spectra and elemental analysis. Preliminary results show that none of the synthesized benzimidazole derivatives has antifungal activity at the concentration of 100 micrograms/ml against Candida parapsilosis, Candida stellatoidea, and Candida pseudotropicalis.