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Improvement of a Vero cell assay to determine diphtheria antitoxin content in sera
1State Serum Institute, Bacteria Vaccine Department, Copenhagen S, Denmark.
Abstract:
Diphtheria antitoxin content in sera were determined automatically in Vero cell assay by spectrophotometric determination of the equivalence point between toxin and antitoxin followed by computer analysis of absorption values. The method was more accurate than visual reading and made handling of many samples easy.