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The QKd interval in panic disorder: an assessment of end-organ thyroid hormone responsivity
M B Stein1, J Muir-Nash, T W Uhde
1Section on Anxiety and Affective Disorders, Biological Psychiatry Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892.
Biological Psychiatry
|June 15, 1991
Abstract:
The QKd interval was utilized as a presumptive index of end-organ thyroid hormone effect to test the hypothesis that patients with panic disorder might have abnormal tissue-level responsivity to normal levels of peripherally circulating thyroid hormones. No significant differences in QKd intervals were found between 15 patients with panic disorder (230 +/- 50 msec) and 20 normal controls (224 +/- 29 msec) while drug-free. These findings suggest that patients with panic disorder have normal tissue-level responsivity to thyroid hormone.