Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hemodynamics and exercise capacity during pacemaker stimulation.

R Nordlander1, A Hedman

  • 1Division of Cardiology, Karolinska Hospital, Stockholm, Sweden.

Herz
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cohort study of serological biomarkers for interstitial lung disease in patients with rheumatoid arthritis.

Scandinavian journal of rheumatology·2024
Same author

Rapid breakthrough of <sup>131</sup>I in an in vitro human epidermis model.

Toxicology in vitro : an international journal published in association with BIBRA·2017
Same author

Corrigendum. Patterns of functioning in older adults with mild cognitive impairment: a two-year study focusing on everyday technology use.

Aging & mental health·2015
Same author

Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety.

Diabetologia·2012
Same author

Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer.

Gene therapy·2009
Same author

Are predictors for myocardial infarction the same for women and men when evaluated prior to hospital admission?

International journal of cardiology·2005
Same journal

[Advancing cardiovascular prevention : Evidence-based design of healthy and sustainable food environments].

Herz·2026
Same journal

[Effects of air pollution on cardiovascular health].

Herz·2026
Same journal

[Heart and climate].

Herz·2026
Same journal

Multidimensional psychosocial screening in routine cardiac care: preliminary findings from a cross-sectional survey.

Herz·2026
Same journal

[Noise and the heart].

Herz·2026
Same journal

[The cardiovascular exposome: areas of action for prevention and practical cardiology].

Herz·2026
See all related articles

Restoring heart rate variability is key for pacemaker patients, improving cardiac output and exercise tolerance. Atrioventricular synchronization offers additional benefits, particularly at rest, enhancing overall cardiac function.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Physiology

Background:

  • Pacemaker technology significantly impacts cardiovascular function.
  • Understanding hemodynamic and myocardial effects of pacing is crucial for patient outcomes.
  • Heart rate variability and atrioventricular synchronization are key considerations in pacing.

Purpose of the Study:

  • To review the hemodynamic and myocardial effects of different pacing modalities.
  • To assess the roles of heart rate variability and atrioventricular synchronization.
  • To evaluate the impact of pacing on cardiac output and exercise tolerance.

Main Methods:

  • Literature review of studies on pacing modalities.
  • Analysis of hemodynamic parameters (cardiac output, heart rate).

Related Experiment Videos

  • Assessment of myocardial oxygen consumption and sympathetic activity.

    • Main Results:

    • Adequate heart rate increase is critical for cardiac output and exercise tolerance, regardless of atrioventricular synchronization.
    • Atrioventricular synchronization provides hemodynamic benefits, especially at rest.
    • Rate-adaptive pacing demonstrates more "economic" cardiac work and may mitigate negative long-term effects compared to fixed-rate pacing.

    Conclusions:

    • Restored rate variability benefits most pacemaker-dependent patients.
    • Atrial electrograms are optimal triggers for rate-adaptive pacing.
    • Alternative rate-triggering signals can yield comparable hemodynamic and exercise tolerance results when atrial signals are unreliable.