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Formula predicting survival in mice inoculated with leukemia cells
1Department of Pathology, Morristown-Hamblen Hospital, Morristown, TN 37814.
Abstract:
A microcomputer program in BASIC for predicting the survival probability after inoculation of L1210 leukemia cells into mice is designed. Formulas used in this study are derived from the data published by Johnson et al. (J Natl Cancer Inst, 34 (1965) 277-290). A mathematical model and a computer program previously published by the author are employed in this study. Analysis of the computer-assisted predicted values and the reported data (J Natl Cancer Inst, 34 (1965) 277-290) on survival probabilities has shown that the program is accurate and reliable with a close agreement in expressing survival probability as a function of inoculum size and time after inoculation.