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Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
Infections in British clinical laboratories, 1988-1989
1University of Glasgow.
Abstract:
During 1988-89 this continuing survey showed 18 infections in the staff of laboratories reporting from 166 centres, representing 21,756 person-years of exposure. Shigella and other bowel infections (one caused by S typhi) predominated, affecting 11 microbiology medical laboratory scientific officers. Three shigella infections originated from quality control samples. Pulmonary tuberculosis affected four workers, including two mortuary technicians, but without detected occupational exposure to Mycobacterium tuberculosis. Other infections included one caused by Brucella melitensis. Hepatitis was not reported. The sustained low level of hepatitis is encouraging and suggests a low risk to staff of bloodborne infections such as human immunodeficiency virus.
Insights
Laboratory staff experienced 18 infections, primarily Shigella and bowel infections, over 21,756 person-years. Tuberculosis and Brucella melitensis were also reported, with low hepatitis incidence suggesting reduced bloodborne infection risk.
Area of Science:
- Occupational Health
- Infectious Disease Epidemiology
- Laboratory Safety
Background:
- Laboratory personnel face risks of infection from various pathogens.
- Monitoring infection rates is crucial for assessing occupational hazards in healthcare settings.
Purpose of the Study:
- To assess the incidence and types of infections among laboratory staff.
- To evaluate the effectiveness of safety measures in preventing occupational infections.
Main Methods:
- A continuing survey conducted during 1988-89.
- Data collected from 166 laboratories, covering 21,756 person-years of exposure.
- Infection types and sources were documented.
Main Results:
- 18 infections were reported among laboratory staff.
- Shigella and other bowel infections predominated (11 cases), including one Salmonella typhi.
- Four cases of pulmonary tuberculosis and one Brucella melitensis infection were noted.
Conclusions:
- Bowel infections, particularly Shigella, represent a significant occupational risk.
- Low reported hepatitis incidence suggests effective control of bloodborne pathogens.
- Continued surveillance is necessary to ensure laboratory worker safety.
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