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HTLV-I neurotropism. In vitro studies
1Department of Experimental Medicine and Biochemical Science, University of Rome, Italy.
Acta Neurologica
|April 1, 1991
Abstract:
The human T cell leukemia lymphoma virus (HTLV-I) has been recently associated to neurological disorders. In order to investigate the interaction between this virus and the central nervous system, cells of neuroectodermic origin have been exposed to HTLV-I through an experimental in vitro model. The results revealed the presence of HTLV-I virus core protein p19 inside glial cells, after a short time exposure to a chronically infected donor cell line. This suggests a possible role of a lymphotropic retrovirus in neurological diseases.