Primate cathelicidin orthologues display different structures and membrane interactions

Francesca Morgera1, Lisa Vaccari, Nikolinka Antcheva

  • 1Department of Life Sciences, University of Trieste, 34127 Trieste, Italy. francesca.morgera@elettra.trieste.it

The Biochemical Journal
|October 17, 2008
PubMed
Summary

Primate cathelicidin variations affect how peptides interact with cell membranes. Monomeric forms offer direct antibacterial action, while aggregated forms gain host-cell modulating functions.

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