Related Experiment Video
Updated: Jun 28, 2026

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
Can ROTEM thromboelastometry predict postoperative bleeding after cardiac surgery?
Simon J Davidson1, Donovan McGrowder, Michael Roughton
1Department of Haematology, Royal Bromptom Hospital, London, UK. s.davidson@rbht.nhs.uk
Objective:
To evaluate the predictive ability of ROTEM thromboelastometry (Pentapharm, Basel, Switzerland) to identify patients bleeding more than 200 mL/h in the early postoperative period after cardiac surgery.
Design:
A prospective observational study.
Setting:
A single university hospital.
Participants:
Fifty-eight adult male and female patients undergoing primary coronary artery revascularization.
Interventions:
Blood samples taken preoperatively and at 1, 2, and 3 hours after surgery.
Measurements And Main Results:
Eight patients bled at least 200 mL/h in the study period. All (100%) had at least 1 abnormal ROTEM result in the study period. Of the 49 patients not found to be bleeding more than 200 mL/h in any of the first 4 postoperative hours, 46 (94%) had at least 1 abnormal ROTEM result. The positive and negative predictive values were 14.8% and 100%, respectively.
Conclusions:
ROTEM thromboelastometry has poor predictive utility to identify patients who bleed more than 200 mL/h in the early postoperative period after cardiac surgery. However, its negative predictive value was good.