Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 28, 2026

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
04:48

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

Published on: November 28, 2018

Can ROTEM thromboelastometry predict postoperative bleeding after cardiac surgery?

Simon J Davidson1, Donovan McGrowder, Michael Roughton

  • 1Department of Haematology, Royal Bromptom Hospital, London, UK. s.davidson@rbht.nhs.uk

Journal of Cardiothoracic and Vascular Anesthesia
|October 17, 2008
PubMed
Summary

Rotational thromboelastometry (ROTEM) has poor predictive ability for identifying patients with significant postoperative bleeding after cardiac surgery. However, ROTEM demonstrated a good negative predictive value in this study.

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and safety of dabrafenib plus trametinib in adults with differentiated thyroid cancer: a randomised, double-blind, placebo-controlled, phase 3 trial.

The Lancet. Oncology·2026
Same author

Toward Precision in Myocardial Injury Management: A Critical Synthesis and the C.A.L.I.B.R.A.T.E. Framework for Biomarker Integration.

Clinical Medicine Insights. Cardiology·2026
Same author

Dabrafenib in pediatric patients with <i>BRAF</i> V600 mutation-positive high-grade glioma: Results from a phase 1/2a single-arm study.

Neuro-oncology practice·2025
Same author

Nitric Oxide in the Treatment of COVID-19: Nasal Sprays, Inhalants and Nanoparticles.

Biochemistry research international·2025
Same author

The Differential Modulatory Effects of Potassium Supplementation on Blood Pressure, Vascular Reactivity, Glomerular Filtration Rates, and Oxidative Stress in Different Experimental Hypertensive Models.

Nutrients·2025
Same author

Dabrafenib, alone or in combination with trametinib, in BRAF V600-mutated pediatric Langerhans cell histiocytosis.

Blood advances·2023

Area of Science:

  • Anesthesiology
  • Cardiovascular Surgery
  • Critical Care Medicine
  • Hematology

Background:

  • Postoperative bleeding is a significant complication following cardiac surgery.
  • Accurate identification of patients at risk for excessive bleeding is crucial for timely intervention.
  • Rotational thromboelastometry (ROTEM) is a viscoelastic hemostasis analysis method.

Purpose of the Study:

  • To assess the predictive capability of ROTEM for identifying patients with bleeding exceeding 200 mL/h post-cardiac surgery.
  • To evaluate ROTEM's utility in the early postoperative period.

Main Methods:

  • Prospective observational study conducted at a single university hospital.
  • Included 58 adult patients undergoing primary coronary artery revascularization.

Related Experiment Videos

Last Updated: Jun 28, 2026

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
04:48

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

Published on: November 28, 2018

  • Blood samples analyzed preoperatively and at 1, 2, and 3 hours post-surgery.
  • Main Results:

    • Eight patients (13.8%) experienced bleeding of at least 200 mL/h.
    • All bleeding patients had at least one abnormal ROTEM result (100% sensitivity).
    • The negative predictive value of ROTEM was 100%, while the positive predictive value was 14.8%.

    Conclusions:

    • ROTEM exhibits poor predictive utility for identifying patients with significant early postoperative bleeding after cardiac surgery.
    • Despite poor positive predictive value, ROTEM demonstrated a strong negative predictive value, suggesting its utility in ruling out significant bleeding.