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Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
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Published on: January 17, 2025

Human angiostrongyliasis.

Qiao-Ping Wang1, De-Hua Lai, Xing-Quan Zhu

  • 1Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.

The Lancet. Infectious Diseases
|October 17, 2008
PubMed
Summary
This summary is machine-generated.

Human angiostrongyliasis, a rat lungworm infection, is a growing global concern. Prevention requires public education on avoiding raw or undercooked hosts to control this foodborne zoonotic disease.

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Area of Science:

  • Parasitology
  • Zoonotic Diseases
  • Public Health

Background:

  • Human angiostrongyliasis is caused by Angiostrongylus cantonensis, a rat lungworm.
  • Infections occur through ingestion of raw or undercooked intermediate/paratenic hosts or contaminated produce.
  • Over 2827 cases are documented globally, with recent outbreaks in China, Taiwan, and the USA.

Purpose of the Study:

  • To review the clinical features, diagnosis, and treatment of human angiostrongyliasis.
  • To describe the geographical distribution and prevalence of Angiostrongylus cantonensis.
  • To emphasize public education for disease prevention and control.

Main Methods:

  • Literature review of clinical cases and epidemiological data.
  • Analysis of reported outbreaks and sporadic cases.
  • Synthesis of information on Angiostrongylus cantonensis distribution.

Main Results:

  • Human angiostrongyliasis is a globally reported disease with increasing incidence.
  • Outbreaks and travel-related cases highlight its expanding reach.
  • Clinical manifestations, diagnostic methods, and treatment options have been documented.

Conclusions:

  • Angiostrongylus cantonensis poses a significant foodborne zoonotic threat.
  • Public awareness regarding consumption of raw or undercooked hosts is crucial for prevention.
  • Continued surveillance and education are essential for controlling human angiostrongyliasis.