Related Experiment Video
Updated: Jun 28, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Risk factors for repeat adverse asthma events in children after visiting an emergency department
Teresa To1, Chengning Wang, Sharon Dell
1Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada. teresa.to@sickkids.ca
Insights
Children with asthma visiting the emergency department (ED) showed improved outcomes at six months. Drug insurance and regular bed linen washing were linked to fewer asthma episodes and ED visits.
Area of Science:
- Pediatric Pulmonology
- Public Health
- Health Services Research
Background:
- Asthma is a common chronic respiratory disease in children.
- Emergency department (ED) visits for pediatric asthma represent a significant healthcare burden.
- Identifying factors influencing long-term outcomes post-ED care is crucial for effective management.
Purpose of the Study:
- To identify risk factors for adverse long-term asthma outcomes in children after ED visits.
- To assess the impact of drug insurance coverage on pediatric asthma management.
- To evaluate trends in acute asthma episodes and ED utilization post-discharge.
Main Methods:
- Prospective observational study at a pediatric tertiary hospital ED in Ontario, Canada.
- Outcomes (acute asthma episodes, ED visits) tracked at baseline, 1, and 6 months post-discharge.
- Generalized estimating equations and logistic regression analyzed outcome trends and risk factors.
Main Results:
- 81.8% of 269 children completed follow-up; ED use decreased significantly by 6 months (39.4% to 26.8%).
- Children with drug insurance had fewer acute asthma episodes (AOR=0.36) and repeat ED visits (AOR=0.45).
- Previous asthma events and infections were risk factors; weekly hot water linen washing was protective.
Conclusions:
- Pediatric asthma patients showed improved long-term outcomes after ED care.
- Identified risk factors, including lack of insurance, can target interventions for vulnerable populations.
- Strategies should focus on maximizing insurance coverage and enhancing asthma self-management education.
Objective:
The aim of this study was to identify risk factors for long-term adverse outcomes in children with asthma after visiting the emergency department (ED).
Methods:
A prospective observational study was conducted at the ED of a pediatric tertiary hospital in Ontario, Canada. Patient outcomes (ie, acute asthma episodes and ED visits) were measured at baseline and at 1- and 6-months post-ED discharge. Time trends in outcomes were assessed using the generalized estimating equations method. Multiple conditional logistic regressions were used to model outcomes at 6 months and examine the impact of drug insurance coverage while adjusting for confounders.
Results:
Of the 269 children recruited, 81.8% completed both follow-ups. ED use significantly reduced from 39.4% at baseline to 26.8% at 6 months (P < .001), whereas the level of acute asthma episodes remained unchanged. Children with drug insurance coverage were less likely to have acute asthma episodes (adjusted odds ratio [AOR] = 0.36; 95% CI, 0.15-0.85; P < .02) or repeat ED visits (AOR = 0.45; 95% CI, 0.20-0.99; P < .05) at 6 months. Other risk factors for adverse outcomes included previous adverse asthma events and certain asthma triggers (eg, cold/sinus infection). Washing bed linens in hot water weekly was protective against subsequent acute asthma episodes.
Conclusions:
Our study demonstrated significant improvements in long-term outcomes in children seeking acute care for asthma in the ED. Future efforts remain in targeting the sustainability of improved outcomes beyond 6 months. Risk factors identified can help target vulnerable populations for proper interventions, which may include efforts to maximize insurance coverage for asthma medications and strategies to improve asthma self-management through patient and provider education.
Related Concept Videos
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma I: Introduction
Asthma III: Clinical Manifestations
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
