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Updated: Jun 28, 2026

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Evaluation of the disk diffusion method compared to the microdilution method in susceptibility testing of
Carmelo Massimo Maida1, Maria Eleonora Milici, Laura Trovato
1Istituto di Malattie Infettive e Medicina Pubblica, Università Politecnica delle Marche, Azienda Ospedaliera-Universitaria, Ospedali Riuniti, Torrette di Ancona, Ancona, Italy.
Abstract:
Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-microg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.
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