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Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
Ventilatory Modes01:14

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...

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Erratum to: Laryngeal transplantation in minipigs: vascular, myologic and functional outcomes.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2016
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Related Experiment Video

Updated: Jun 28, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
09:31

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Published on: February 14, 2022

Artificial lung: current perspectives.

T Go1, P Macchiarini

  • 1Department of General Thoracic, Surgery Hospital Clinic, University of Barcelona, Barcelona, Spain.

Minerva Chirurgica
|October 17, 2008
PubMed
Summary
This summary is machine-generated.

Artificial lungs offer a promising alternative to mechanical ventilation for severe lung disease. Recent technological advancements, like low-resistance oxygenators, are improving artificial lung development for respiratory failure patients.

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Implantation of Fibrin Gel on Mouse Lung to Study Lung-specific Angiogenesis

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Related Experiment Videos

Last Updated: Jun 28, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
09:31

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Published on: February 14, 2022

Transplantation of Bioengineered Lung Using Decellularized Mouse Lungs and Primary Human Endothelial Cells
10:13

Transplantation of Bioengineered Lung Using Decellularized Mouse Lungs and Primary Human Endothelial Cells

Published on: March 28, 2025

Implantation of Fibrin Gel on Mouse Lung to Study Lung-specific Angiogenesis
07:52

Implantation of Fibrin Gel on Mouse Lung to Study Lung-specific Angiogenesis

Published on: December 21, 2014

Area of Science:

  • Biomedical Engineering
  • Respiratory Medicine
  • Critical Care

Background:

  • Increasing prevalence of end-stage pulmonary disease necessitates advanced respiratory support.
  • Mechanical ventilation, while common, carries risks of lung damage and is often insufficient for acute respiratory distress syndrome, chronic respiratory failure, and lung transplantation.
  • Existing extracorporeal lung assist devices present challenges including transfusion needs, complexity, and infection risk.

Purpose of the Study:

  • To review the current status and advancements in artificial lung technology.
  • To highlight the limitations of current mechanical ventilation and extracorporeal support systems.
  • To discuss the impact of new technologies on the development of artificial lungs.

Main Methods:

  • Review of current literature and technological developments in artificial lung systems.
  • Analysis of the challenges and successes of existing extracorporeal membrane oxygenation and lung assist devices.
  • Examination of recent innovations, particularly low-resistance oxygenators.

Main Results:

  • Development of artificial lungs has lagged behind cardiac and renal support systems due to technological limitations.
  • New technologies, especially low-resistance oxygenators, are enabling significant progress in artificial lung development.
  • Artificial lungs represent a new stage in managing severe respiratory failure.

Conclusions:

  • Artificial lungs are crucial for addressing the limitations of mechanical ventilation in severe lung disease.
  • Technological innovations are driving the advancement of artificial lung systems.
  • The review provides an overview of the current state and future potential of artificial lungs.